Morbidity of Stereotactic Biopsy for Intracranial Lesions

概要

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The safety of stereotactic biopsy (STB) was studied in this article. CT-guided STB(Brown-Roberts-Wells; BRW) was performed 58 times for 56 patients (male: 29,female: 27) at Hyogo Cancer Center between 1988 and 2007. The age distributionranged from 15 to 83 (mean: 55) years old. Histological diagnoses were established for58 samples, with 35 cases of glioma, eight of metastatic brain tumor, nine of malignantlymphoma and leukemia, two of germ cell tumor, two of abscess, one necrosis, and onecase with normal tissue. There were 3 cases (5.2%) in which an intratumoralhemorrhage with neurological deficits was occurred. They were needed surgicallyremoval and those histological pathology revealed glioma. Concerning location ofbiopsy, STB for basal ganglia (putamen or globus pallidus) and thalamus were causedcomplication of the intratumoral hematoma after biopsy. The review of the 575 casesindicates that glioma was the relative risk factor for morbidity associated with CTguidedSTB (odds ratio 5.36). The overall morbidity rate was 6.4% (37/575). Weconsidered that tumors of the basal ganglia (putamen or globus pallidus), thalamus andglioma were risk factors of morbidity for CT-guided STB.
神戸大学の論文
2010-00-00