Growth of Endothelial Cells on Surfaces Modified by a Plasma-Polymerized Coating(Organic Molecular Electronics)
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概要
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Endothelial cell adhesion and growth were investigated on three types of surfaces with a plasma-polymerized coating (PPC): (1) the pristine surface of a hexamethyldisiloxane (HMDS) PPC (hydrophobic, electrically neutral surface); (2) an HMDS PPC surface with nitrogencontaining plasma treatment (hydrophilic, positively charged surface); and (3) an HMDS PPC surface treated with oxygen plasma (hydrophilic, negatively charged surface). Endothelial cells grew on surface (2) but not on surfaces (1) or (3). Next, endothelial cell adhesion and growth was investigated on a surface on which 80-μm squares were micro-patterned at 160-μm intervals in a mosaic composed of two different (cell-adhesive and non-cell-adhesive) regions. Cell growth on the patterned surfaces was different from that on non-patterned surfaces. PPC was shown to be a simple process for modulating cell adhesion to surfaces.
- 社団法人電子情報通信学会の論文
- 2007-09-01
著者
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Kudo Susumu
Department Of Mechanical Engineering Shibaura Institute Of Technology
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Kawasaki Naoto
Department Of Mechanical Engineering Shibaura Institute Of Technology
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MUGURUMA Hitoshi
Department of Electronic Engineering, Shibaura Institute of Technology
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Murata Naoya
Department Of Electronic Engineering Shibaura Institute Of Technology
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Muguruma Hitoshi
Department Of Electronic Engineering Shibaura Institute Of Technology
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Muguruma Hitoshi
Department Of Electrical And Electronics Engineering Tokyo Institute Of Technology
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KURETOKO Shogo
Department of Mechanical Engineering, Shibaura Institute of Technology
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Kuretoko Shogo
Department Of Mechanical Engineering Shibaura Institute Of Technology
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Kudo Susumu
Department of Engineering, Shibaura Institute of Technology
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