Amperometric Biosensor Based on Carbon Nanotube Functionalized by Redox Plasma-Polymerized Film
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概要
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A novel fabrication approach for the amperometric biosensor based on multilayer films containing carbon nanotubes (CNT), a plasma-polymerized film (PPF), and enzyme glucose oxidase (GOD) is reported. The configuration of the electrochemical electrode is sequentially composed of sputtered gold, lower acetonitrile PPF, CNT, redox PPF, GOD, and upper acetonitrile PPF (denoted as PPF/GOD/Redox-PPF/CNT/PPF/Au). The lower acetonitrile PPF deposited on Au acts as a permselective membrane, and as a scaffold for CNT layer formation. The upper acetonirile PPF directly deposited on GOD acts as a matrix for enzyme immobilization. The redox PPF polymerized by a monomer of dimethlyaminomethlyferrocene (DAF) is directly deposited onto CNTs. The surface of the functionalized CNT has redox sites of ferrocene groups that shuttle electrons from CNTs to the sensing surface of the Au electrode. The synergy between the redox PPF and CNT provides benefits in terms of lowering the operational potential and enhancing the sensitivity (current). The optimized glucose biosensor revealed a sensitivity of 2.0 μA mM-1 cm-2 at +0.4 V vs Ag/AgCl, a linear dynamic range of 4.9--27 mM, and a response time of 5 s.
- 2011-08-25
著者
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Muguruma Hitoshi
Department Of Electrical And Electronics Engineering Tokyo Institute Of Technology
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HOSHINO Tatsuya
Department of Electronic Engineering, Shibaura Institute of Technology
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Hoshino Tatsuya
Department of Electronic Engineering, Shibaura Institute of Technology, Koto, Tokyo 135-8548, Japan
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Muguruma Hitoshi
Department of Electronic Engineering, Shibaura Institute of Technology, Koto, Tokyo 135-8548, Japan
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