Diabetes Mellitus Does Not Affect Jugular Bulb Oxygen Saturation in Patients Undergoing Off-Pump Coronary Artery Bypass Graft Surgery
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概要
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Background Diabetes mellitus (DM) is associated with the impairment of cerebral oxygenation during cardiac surgery. The aim of the present study was to investigate the effects of DM on cerebral oxygenation assessed by jugular bulb oxygen saturation (SjvO_2) in patients undergoing off-pump coronary artery bypass graft surgery (OPCAB) in a prospective controlled trial. Methods and Results Twenty-three diabetic patients with glycosylated hemoglobin above 7.0% (DM group) and 23 non-diabetic patients (control group) undergoing OPCAB with no-touch aortic technique were included. A fiberoptic oximetry catheter was inserted into the jugular bulb. The lowest SjvO_2 and the number of patients with cerebral desaturation, defined as SjvO_2 less than 50% over 5min, were recorded during coronary grafting. Three neurocognitive tests were done before surgery and at postoperative day 2 and 7. There were no differences in SjvO_2 between the groups. Furthermore, the number of patients with cerebral desaturation and all neurocognitive test scores were similar between the 2 groups. None of the patients developed neurocognitive dysfunction. Conclusions Cerebral oxygenation in diabetic patients was similar to that of non-diabetic patients and well maintained above the critical level without resulting in clinically significant postoperative neurocognitive dysfunction during OPCAB with no-touch aortic technique.
- 社団法人日本循環器学会の論文
- 2008-07-20
著者
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LEE Jong
Department of Polymer Science and Engineering, Kumoh National Institute of Technology
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KIM Ji
Department of Polymer Science and Engineering, Kumoh National Institute of Technology
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YOO Kyung
Department of Thoracic and Cardiovascular Surgery, Yonsei Cardiovascular Hospital, Yonsei University
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SHIM Jae
Department of Food and Nutrition, Seoul National University
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Shim Jae
Department Of Anesthesiology And Pain Medicine Yonsei University College Of Medicine
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Shim Jae
Department Of Anesthesiology And Pain Medicine Yonsei University College Of Medicine:anesthesia And
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KWAK Young
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
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Oh Young
Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
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Kim Ji
Department Of Anesthesiology And Pain Medicine Gachon Medical School Gil Medical Center
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Oh Young
Department Of Anesthesiology And Pain Medicine Yonsei University College Of Medicine:anesthesia And
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Yoo Kyung
Department Of Thoracic And Cardiovascular Surgery Yonsei University College Of Medicine
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Kwak Young
Department Of Anesthesiology And Pain Medicine Yonsei University College Of Medicine
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Kwak Young
Department Of Anesthesiology And Pain Medicine Yonsei University College Of Medicine:anesthesia And
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Yoo Kyung
Department Of Anesthesiology Chonnam National University Medical School
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Lee Jong
Department Of Anesthesiology And Pain Medicine Dong-a University Hospital
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Lee Jong
Department Of Anesthesiology And Pain Medicine Yonsei University College Of Medicine:anesthesia And
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Lee Jong
Depart. Of Oncology Yonsei Univ. Wonju College Of Medicine
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Kwak Young
Department Of Anesthesiology And Pain Medicine Anesthesia And Pain Research Institute Yonsei University College Of Medicine
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Shim Jae
Department Of Anesthesiology And Pain Medicine Anesthesia And Pain Research Institute Yonsei University College Of Medicine
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Kim Ji
Department of Advanced Materials Engineering, Sangju National University, Kyeongbuk 742-711, Korea
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