The Electrophilic Reaction of Methylacridine Derivatives with Aniline
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概要
- 論文の詳細を見る
The mixture of acridine hydrochloride and aniline in the reaction tube under N_2 gas was heated without solvent at 110℃ for 5hr, and then the reaction products were obtained as 9-(4-aminophenyl)-acridine. We synthesized four kinds of methylacridine hydrochlorides. The reactions of methylacridine hydrochlorides with aniline without solvent in the reaction temperature range from 100℃ to 150℃ also produced 9-(4-aminophenyl)-methylacridines as the reaction products. The yields of 9-(4-aminophenyl)-methylacridines depended heavily on the position of a methyl group of methylacridines. As the heat of formation of the product was increased, the yield of reaction product was decreased. The yield of reaction product was related to the stability of reaction product.
- 東海大学の論文
著者
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Takano Jiro
Department Of Biology School Of Education Waseda University
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Ishihara Yoshimi
Department of Chemistry, School of Science, Tokai University
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Ishihara Yoshimi
Department Of Chemistry School Of Science Tokai University
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Saito Hiroshi
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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ITO Takeyuki
Department of Chemistry, School of Science, Tokai University
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Ito Takeyuki
Department Of Chemistry School Of Science Tokai University
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Saito Hiroshi
Department of Applied Chemistry, Graduate School of Engineering, Tohoku University
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