Factors Influencing Cardiopulmonary Exercise Testing in Obstructive Sleep Apnea Syndrome Patients

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概要

• 論文の詳細を見る

• The exercise capacity of obstructive sleep apnea syndrome (OSAS) patients has been demonstrated to be impaired, but the factors responsible are still unclear. In addition, ventilatory efficiency during exercise has never been studied in OSAS. Hypertension (HT), commonly found in OSAS patients, could be a contributing factor to exercise capacity. The aim of the study is: 1) to determine possible factors that could influence the exercise in OSAS patients, and 2) to compare the exercise capacity and ventilatory efficiency of patients with and without HT. Twenty-two male OSAS patients were submitted to cardiopulmonary exercise testing. Multiple linear regression analyses were used to find possible factors that could influence the exercise capacity and ventilatory efficiency of OSAS patients. Patients were divided into two groups according to the presence of HT, and cardiopulmonary exercise testing (CPET) results were compared between them. No factors emerged as predictors of oxygen consumption at peak exercise (FOipeak). The slope of increase of ventilation relative to carbon dioxide production (FE/FCOi-slope) was associated with body mass index (BMI) negatively and with apneahypopnea index (AHI) positively (p = 0.019 and p =0.047, respectively). There were no differences in either FOipeak or anaerobic threshold (AT) between OSAS with and without HT, but the FE/FCOi-slope was higher in the HT group (p = 0.008). Our results suggest that the severity of sleep apnea can influence the ventilatory efficiency of OSAS patients along with BMI and HT.

• 新潟大学の論文

著者

• GEJYO Fumitake

  Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences

• Gejyo F

  Division Of Respiratory Medicine Department Of Homeostatic Regulation And Development Course In Biol

• TAKADA Toshinori

  Division of Respiratory Medicine, Department of Homeostatic Regulation and Development, Course in Bi

• AKAZAWA Kohei

  Department of Medical Informatics, Niigata University Medical and Dental Hospital

• Tsukada Hiroki

  Division Of Clinical Infection Control And Prevention Niigata University Graduate School Of Medical

• Nakayama Hideaki

  Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences

• MATSUYAMA Naho

  Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences

• SAKAI Kunihiko

  Department of Pathology, Osaka Koseinenkin Hospital

• Akazawa Kohei

  新潟大学 医歯学総合研究科呼吸器内科

• Gejyo Fumitake

  Department Of Medicine Iigata University School Of Medicine

• Sakai Kunihiko

  Departmanets Of Respiratory Medicine Nishi-niigata Chuo National Hospital

• Matsuyama Naho

  Division Of Respiratory Medicine Graduate School Of Medical And Dental Sciences Niigata University

• Takada Toshinori

  Division Of Respiratory Medicine Department Of Homeostatic Regulation And Development Course In Biol

• Yamabayashi Cristiane

  Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University

• Watanabe Takeo

  Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University

• Ohdaira Tetsuro

  Departmanets of Respiratory Medicine, Nishi-Niigata Chuo National Hospital

• Kobayashi Kuriko

  Departmanets of Medical Informatics, Niigata University Medical and Dental Hospital

• Nakayama Hideaki

  Division Of Respiratory Medicine Graduate School Of Medical And Dental Sciences Niigata University

• Yamabayashi Cristiane

  Division Of Respiratory Medicine Graduate School Of Medical And Dental Sciences Niigata University

• Akazawa Kohei

  Departmanets Of Medical Informatics Niigata University Medical And Dental Hospital

• Kobayashi Kuriko

  Niigata Univ. Graduate School Of Medical And Dental Sci.

• Gejyo Fumitake

  Division Of Respiratory Medicine Graduate School Of Medical And Dental Sciences Niigata University

• Gejyo Fumitake

  Division Of Clinical Infection Control And Prevention Niigata University Graduate School Of Medical

• Ohdaira Tetsuro

  Departmanets Of Respiratory Medicine Nishi-niigata Chuo National Hospital

• Watanabe Takeo

  Division Of Respiratory Medicine Graduate School Of Medical And Dental Sciences Niigata University

• Matsuyama Naho

  Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University

• Gejyo Fumitake

  Division of Clinical Nephrology and Rheumatology, Graduate School of Medical and Dental Sciences, Niigata University

• Gejyo Fumitake

  Division of Respiratory Medicine, Graduate School of Medical and Dental Sciences, Niigata University

• Akazawa Kohei

  Departmanets of Medical Informatics, Niigata University Medical and Dental Hospital

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