歯肉炎ならびに辺縁性歯周炎患者唾液のプロテアーゼ活性,上皮細胞数と歯石指数との相関について

概要

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We have already reported the positive correlation between calculus index and the protease activities in whole saliva. The purpose of this paper was to determine the origin of the proteases. The saliva was collected in the siliconized tubes from the patients with gingivitis or marginal periodontitis before and after oral prophylaxis. The numbers of leukocyte and epithelial cell in the saliva were counted. The protease activity was determined by a fluorophotometer using hemoglobin as a substrate. The protease activity was not detectable in parotid saliva, but a little in submaxillary saliva. However, the activity was observed in the whole saliva from edentulous persons. The oral prophylaxis reduced the protease activity (pH 8.5), the number of leukocyte and epithelial cell and calcium concentration. The positive significant correlation was observed between the protease activity and the number of epithelial cell, not of leukocyte. These results suggest that the epithelial cell is a main source of the salivary protease.
特定非営利活動法人日本歯周病学会の論文
1980-06-28