1234 表面形状が人工関節固定性に及ぼす影響のin vitro評価(G02-5 関節と軟骨(2),G02 バイオエンジニアリング)

概要

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Effect of the surface topography on the adhesion of the artificial joint was evaluated in vitro. Alumina plates with beads and honeycomb structural surface were prepared as specimen. Bone marrow-derived mesenchymal stem cells were seeded on the surface of the bone plate and the alumina plates. After cultivation, the shear test was carried out to mesure the adhesive strength between the bone plate and the alumina plates. Quantitative mesurment of alkaline phosphatase activity, DNA and Ca amount were measured quantitatively and the surface of the alumina plate was observed by scanning electron microscope. The result showed that the surface topography affected activity of osteoblast and adhesion of the artificial joint.
社団法人日本機械学会の論文
2005-09-18