Design and Synthesis of Dioxetane-Based Chemiluminescent Substrates with High Efficiency in Aqueous System(By a grant Research Institute for Integrated Science, Kanagawa University)
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概要
- 論文の詳細を見る
The chemiluminescent efficiency of hydroxyphenyl-substituted dioxetanes is well known to decrease significantly in an aqueous medium, though more than bioluminescence in an aprotic medium. We investigated here the effect of hydrogen bonding on singlet-chemiexcitation and fluorescence efficiency of the emitter produced for charge-transfer-induced chemiluminescence by the use of dioxetanes bearing a 3-hydroxyphenyl moiety substituted with a proton-donating group at the 4-position as a model substrate. Based on this investigation, four bicyclic dioxetanes bearing a 4-(benzoazol-2-yl)-3-hydroxyphenyl moiety were designed and synthesized. The thus-realized dioxetanes exhibited chemiluminescence with markedly high efficiency in aqueous medium as well as in aprotic medium.
- 神奈川大学の論文
- 2006-05-25
著者
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渡辺 信子
Department Of Chemistry Faculty Of Science Kanagawa University
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大橋 守
Department Of Chemistry Faculty Of Science Kanagawa University
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OHASHI Mamoru
Department of Materials Science, Kanagawa University
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Watanabe Nobuko
Department of Applied Biological Chemistry, Faculty of Agriculture, Meijo University
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Watanabe Nobuko
Department Of Chemistry Faculty Of Science Kanagawa University
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Watanabe Nobuko
Department Of Applied Biological Chemistry Faculty Of Agriculture Meijo University
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MATSUMOTO Masakatsu
Department of Chemistry, Kanagawa University
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Matsumoto Masakatsu
Department Of Chemistry Faculty Of Science Kanagawa University
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松本 主勝
Department Of Chemistry Faculty Of Science Kanagawa University:to Whom Correspondence Should Be Addr
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FUJIMORI Ken
Department of Chemistry, University of Tsukuba
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Fujimori Ken
Department Of Anatomy School Of Medicine Faculty Of Pharmaceutical Sciences Tokushima University
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Fujimori Ken
Department Of Chemistry University Of Tsukuba
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Ohashi Mamoru
Department Of Chemistry Faculty Of Science Kanagawa University
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Ohashi Mamoru
Department Of Applied Physics And Chemistry The University Of Electro-communications
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大橋 守
Department of Chemistry, Faculty of Science, Kanagawa University
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松本 正勝
Department of Chemistry, Kanagawa University
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