Effect of Muramyl Dipeptide on Phagocyte Functions in Rainbow Trout (Oncorhynchus mykiss)

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概要

• 論文の詳細を見る

• The activation of head kidney phagocytes was studied in rainbow trout injected with an immunopotentiator muramyl dipeptide (MDP). Phagocytes showed dose-dependent migratory response to zymosan-treated rainbow trout serum in chemotaxis assay using Nuclepore membrane. Phagocytes of MDP-injected fish showed higher degree of chemotactic response than those from control fish, Phagocytic activity against hydrophilic plastic beads was enhanced when zymosan-treated trout serum was added to cultures. The activity increased after injection of MDP to trout. Increased level of superoxide generation was observed in phagocytes from MDP-injected fish compared with those from control fish when the cells were stimulated either with phorbol 12-myristate 13-acetate, Aeromonas salmonicida cell lysate or opsonized zymosan in cytochrome C reduction test.

• 大阪府立大学の論文
• 1993-03-31

著者

• Mino Masaki

  Department Of Integrated Structural Bioscience Division Of Veterinary Science Graduate School Of Lif

• Azuma Ichiro

  Institute Of Immunological Science Hokkaido University

• Kodama Hiroshi

  Laboratory Of Veterinary Immunology Course Of Veterinary Science Graduate School Of Life And Environ

• Baba Tsuyoshi

  Laboratory Of Veterinary Immunology Department Of Veterinary Science College Of Agriculture

• Kodama Hiroshi

  Laboratory Of Veterinary Immunology Department Of Veterinary Science Science Hokkaido University.

• HIROTA Yoshikatsu

  Laboratory of Veterinary Immunology, Department of Veterinary Science, College of Agriculture

• MUKAMOTO Masafumi

  Laboratory of Veterinary Immunology, Department of Veterinary Science, College of Agriculture

• Azuma Ichiro

  Institute Of Immunological Cience

• Masafumi Mukamoto

  Department Of Integrated Structural Biosciences Division Of Veterinary Science Graduate School Of Life And Environmental Sciences Osaka Prefecture University

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