Clinical Significance of Estrogens in Chronic Aggressive Hepatitis : Estrogen Value in Blood and its Clinical Significance in Patients with Chronic Aggressive Hepatitis

概要

論文の詳細を見る
For a long time, it has been assumed that stagnation of active estrogens in the blood gives rise to liver injury and causes a severe inflammatory process in the liver as well as affecting the clinical course of chronic aggressive hepatitis in women. During the reproductive years, estrogen production, as gaged by urinary excretion values, follows a cyclic pattern. As the menopause is approached, urinary excretion of estrogens gradually diminishes and the cyclic fluctuations become more shallow. The titer continues to fall progressively in the postmenopausal years although some estrogen may be found even in aged women. Even though it must be assumed that estrogens are rarely produced in bilaterally ovariectomized women, chronic aggressive hepatitis is rather frequently encountered in practice in women after ovariectomies to find a solution to the question of whether stagnation of active estrogen in the blood actually gives rise to liver injury, estrogen values in blood must be estimated in these patients. It will be desirable to estimate not the metabolites of estrogens in the urine but estrogens or estrogenic substance themselves in the blood. The author has estimated estrogens in the blood by means of radioimmunoassay and revealed a decrease in quantity of the estrogen value in the blood. Therefore, it can be stressed that lack of estrogens in the blood must be taken into consideration because it has been pointed out that estrogens exert some form of liver-protecting influence against infection as well as the protracting factors of hepatitis.
東海大学の論文

Clinical Significance of Estrogens in Chronic Aggressive Hepatitis : Estrogen Value in Blood and its Clinical Significance in Patients with Chronic Aggressive Hepatitis

スポンサーリンク

概要

著者

関連論文

スポンサーリンク