Amyloidoma, Macroglossia, and Myalgia in AL Amyloidosis

概要

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Fifty one year-old female, visited the hospital with a complaint of myalgia. Myoglobinemia and myoglobinuria were then found. She was found to have a monoclonal light chain of kappa type in the urine without any monoclonal protein in the serum. Proliferated plasma cells of 53.6% was recorded in an aspirated bone marrow. Noted macroglossia with a sharp indentation of the teeth on the edge of the tongue, and tumor at the elbow joint were seen throughout her clinical course. Biopsied materials from the tongue and cubital tumor disclosed deposit of amyloid. She also had amyloidoma of the right elbow region. Thus, a clinical diagnosis was myeloma-associated amyloidosis (AL) with amyloidoma was made. Discussion on amyloidoma in connection with amyloid study was described, since amyloidoma may be a hallmark of amyloidosis.
神戸大学の論文
1997-01-24