Platelet and Cholesterol Responses Caused by Oral Administration ofGinseng Extract in 66% Hepatectomized Rats
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概要
- 論文の詳細を見る
Platelet counts and serum cholesterol levels in the blood were examined after oral administration of ginseng extract (GE) to 66% hepatectomized rats. A significant decrease in the platelet count (PC) and adhesiveness (PA) was obtained 3 days after hepatectomy when GE 125 mg/kg/day was administered, and the PA reduction was dose dependent in the range of 0-250 mg/kg/day. The serum concentration of total cholesterol was also decreased by the GE administration, but food intake was unaffected. Serum parameters indicating liver and kidney functions were unchanged after GE administration except for lipid metabolic parameters. Because enhanced PC and PA in the presence of hypercholesterolemia are apt to lead to thromboembolism after major abdominal surgery, these results suggest that orally administered GE is capable of preventing the thromboembolic tendency associated with major hepatic surgery.
- 新潟大学の論文
著者
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Cui X
Niigata Univ. School Of Medicine Niigata Jpn
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Shirai Y
Niigata Univ. Niigata Jpn
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Shirai Yoshio
Division Of Digestive And General Surgery Department Of Regeneration And Transplant Medicine Niigata
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Xing Cui
The First Department Of Surgery Niigata University School Of Medicine
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Sakaguchi T
Division Of Integrative Physiology Department Of Sensory And Integrative Medicine Niigata University
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Takeo Sakaguchi
The First Department Of Physiology
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Takeo Sakaguchi
The First Department Of Surgery Niigata University School Of Medicine
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Sakaguchi Takeo
Division Of Integrative Physiology Department Of Sensory And Integrative Medicine
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Masahiro OHTAKE
The First Department of Surgery Niigata University School of Medicine
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Ohtake M
Nippon Dental Univ. Niigata Jpn
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Masahiro Ohtake
The First Department Of Surgery
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CUI Xing
The First Department of Surgery, Niigata University School of Medicine
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SAKAGUCHI Takeo
The First Department of Physiology, Niigata University School of Medicine
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OHTAKE Masahiro
The First Department of Surgery Niigata University School of Medicine
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CUI Xing
The First Department of Surgery Niigata University School of Medicine
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