Biochemical Comparison between Radon Effects and Thermal Effects on Humans in Radon Hot Spring Therapy
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概要
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The radioactive and thermal effects of radon hot spring were biochemically compared under a sauna room or hot spring conditions with a similar chemical component, using the parameters that are closely involved in the clinic for radon therapy. The results showed that the radon and thermal therapy enhanced the antioxidation functions, such as the activities of superoxide dismutase (SOD) and catalase, which inhibit lipid peroxidation and total cholesterol produced in the body. Moreover the therapy enhanced concanavalin A (ConA)-induced mitogen response and increased the percentage of CD4 positive cells, which is the marker of helper T cells, and decreased the percentage of CD8 positive cells, which is the common marker of killer T cells and suppressor T cells, in the white blood cell differentiation antigen (CD8/CD4) assay. Furthermore, the therapy increased the levels of α atrial natriuretic polypeptide (αANP), β endorphin, adrenocorticotropic hormone (ACTH), insulin and glucose-6-phosphate dehydrogenase (G-6-PDH), and it decreased the vasopression level. The results were on the whole larger in the radon group than in the thermal group. The findings suggest that radon therapy contributes more to the prevention of life-style-related diseases related to peroxidation reactions and immune suppression than to thermal therapy. Moreover, these indicate what may be a part of the mechanism for the alleviation of hypertension, osteoarthritis (pain), and diabetes mellitus brought about more by radon therapy than by thermal therapy.
- 日本放射線影響学会の論文
著者
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Shibuya Koichi
Chair Of Medical Radioscience
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Shibuya Koichi
岡山大学 医学部放射線医学
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MORI Shuji
Department of Bacteriology, Fukushima Medical College
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Sakai Kazuo
Resarch Center For Radiation Protection National Institute Of Radiological Sciences
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YAMAOKA Kiyonori
Chair of Medical Radioscience
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HANAMOTO Katsumi
Chair of Medical Radioscience
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MITSUNOBU Fumihiro
Misasa Medical Center, Okayama University Medical School
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TANIZAKI Yoshiro
Misasa Medical Center, Okayama University Medical School
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Sakai Kazuo
電中研原子力技術研究所 放射線安全研究センター
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Mori Shuji
Department Of Pharmacology Okayama University Medical School
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Mitsunobu Fumihiro
Misasa Medical Center Okayama University Hospital
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YAMAOKA Kiyonori
Graduate School of Health Sciences, Okayama University
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HANAMOTO Katsumi
Graduate School of Health Sciences, Okayama University
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SUGITA Katsuhiko
Chair of Medical Radioscience
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Sugita Katsuhiro
Chair Of Medical Radioscience
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Hanamoto Katsumi
Graduate School Of Health Sciences Okayama University
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Tanizaki Y
Misasa Medical Center Okayama University Medical School
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Yamaoka Kiyonori
Graduate School Of Health Sciences Okayama University
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Mori Shuji
Department Of Bacteriology Fukushima Medical College
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