A comparative study on effect of continuous radon inhalation on several-time acute alcohol-induced oxidative damages of liver and brain in mouse
スポンサーリンク
概要
- 論文の詳細を見る
We examined the effect of continuous radon inhalation on acute alcohol-induced oxidative damage of mouse liver and brain. Assay of antioxidative functions indicated that lipid peroxide levels in both the liver and brain of the alcohol-treated mice were significantly higher than those of the saline-treated mice. However, the lipid peroxide level in the liver, but not in the brain, of alcohol-treated mice was significantly decreased by radon inhalation whereas that in the brain of saline-treated mice, but not in the liver of saline-treated mice, was significantly increased by radon inhalation. These findings suggest that radon inhalation inhibits alcohol-induced oxidative damage of liver due to activation of antioxidative functions and that radon inhalation exert only a week effect on the brains in comparing with the livers. They further suggest that alcohol administration protects against oxidative damage of the brain that is induced by radon inhalation.
- 日本放射線安全管理学会の論文
著者
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Kataoka Takahiro
Graduate School Of Health Sciences Okayama University
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Kawabe Atsushi
Graduate School Of Health Sciences Okayama University
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Mitsunobu Fumihiro
Misasa Medical Center Okayama University Hospital
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SAKODA Akihiro
Graduate School of Health Sciences, Okayama University
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Sakoda Akihiro
Graduate School Of Health Sciences Okayama University
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Ishimori Yuu
Ningyo-toge Environmental Engineering Center Japan Atomic Energy Agency
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Hanamoto Katsumi
Graduate School Of Health Sciences Okayama University
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Yoshimoto Masaaki
Graduate School Of Health Sciences Okayama University
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Yamaoka Kiyonori
Graduate School Of Health Sciences Okayama University
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Toyota Teruaki
Graduate School Of Health Sciences Okayama University
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KATAOKA Takahiro
Graduate School of Health Sciences, Okayama University
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TOYOTA Teruaki
Graduate School of Health Sciences, Okayama University
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Yamamoto Yuki
Graduate School of Health Sciences, Okayama University
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