嚥下の心拍変動に与える影響の呼吸位相領域における解析

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Heart rate variability has been well studied because of its clinical and physiological importance, along with its overall importance in human engineering. We previously proposed a new method to extract respiratory sinus arrhythmia (RSA) as a waveform in the respiratory phase domain, which can extract RSA with high accuracy. In this paper, we analyze the influence of swallowing on heart rate variability in the respiratory phase domain, and discuss the influence swallowing may have on a general analysis of heart rate variability. The experiment was performed under a 7-minute rest in the sitting position using six subjects. Swallowing was allowed to be performed at the leisure of the subject. We obtained R-R intervals of the electrocardiogram using a sampling frequency of 1 kHz, and respiratory information by sampling the respiration pick-up at the rate of 100 Hz. Further, we put an accelerometer on the larynx and sampled the motion of the laryngeal prominence. Using the mean RSA waveform, it can be seen that swallowing causes tachycardia. Statistical significance was observed between the RSA of the first swallow and RSA without swallowing. The RSA of the next swallow, however, showed no significant difference from the RSA without swallowing. These results show that swallowing causes tachycardia, and that the tachycardia disappears quickly. We can say that this phenomenon exerts an influence on the general analysis of heart rate variability, and respiratory phase domain analysis is an effective method for analyzing external influences such as swallowing on heart rate variability.
社団法人日本生体医工学会の論文
2004-06-10

嚥下の心拍変動に与える影響の呼吸位相領域における解析

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