猫ヘモバルトネラ症に関する研究 : IV. ヘモバルトネラ感染猫の赤血球寿命

概要

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Erythrocyte lifespan was studied in cats infected with Haemobartonella felis, using ^<51>Cr as an isotopic label. Only 5 to 10 per cent of ^<51>Cr-labeled erythrocytes were parasitized with H. felis, though their osmotic fragility increased markedly. For the first 3 days after transfusion of ^<51>Cr-labeled erythrocytes, the amount of labeled erythrocytes destroyed in infected cats was approximately twice that in non-infected cats, while no parasites appeared on any erythrocyte for that period. The average half-life of erythrocytes was 4.3 days in infected cats and 8.8 days in non-infected cats. From the results obtained, it was concluded that erythrocytes were affected so severely with H. felis in infected cats even when the parasite was released from them that their lifespan was impaired.
1975-10-25