Selective Inhibition of Type II Fatty Acid Synthetase by the Antibiotic Thiolactomycin
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概要
- 論文の詳細を見る
The antibiotic thiolactomycin inhibits the fatty acid synthesis from both [1-<14>^C]-acetate and [2-<14>^C]malonyl-CoA of spinach leaves, developing castor bean endosperms and avocado mesocarp. On the other hand, fatty acid synthetases of Brevibacterium ammoniagenes and Corynebacterium glutamicum are much less sensitive to this antibiotic. As has been indicated that thiolactomycin inhibits fatty acid synthetase of Escherichia coli but has little effect on the synthetases of yeast and rat liver [Hayashi et al. (1983) Biochem. Biophys. Res. Commun. 115 : 1108], thiolactomycin is suggested to be a selective inhibitor of type II fatty acid synthetases.
- 日本植物生理学会の論文
著者
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NISHIDA Ikuo
Laboratory of Plant Ecology, Graduate School of Science, Tokyo University
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Nishida I
Tokyo Univ. Tokyo Jpn
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Nishida Ikuo
Department Of Biochemistry And Molecular Biology Saitama University
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Nishida Ikuo
Department Of Biology University Of Tokyo
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Nishida Ikuo
Graduate School Of Science And Engineering Saitama University
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Nishida Ikuo
Univ. Tokyo
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Nishida Ikuo
Department Of Biochemistry And Molecular Biology Faculty Of Science Saitama University
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Kawaguchi Akihiko
Department Of Biology University Of Tokyo
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Yamada Mitsuhiro
Department Of Biology University Of Tokyo
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Yamada Mitsuhiro
Departmellt Of Biology C:ollegc Of Gencral Educatioll Universsity Of Tokyo
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