In Vivo and In Vitro Positive Interference by Cefpirome in Measurement of Serum Creatinine by the Jaffe Method
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概要
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We report the case of an 81-year-old female patient with diverticulitis of the colon, whose symptoms were relieved by intravenous administration of cefpirome. However, her serum creatinine levels were falsely increased by the Jaffe method when serum samples were drawn after intravenous administration of cefpirome. The serum creatinine level in the same sample was within the normal range by the enzymatic method in the automated analyzer. In vitro experiment demonstrated dosedependent positive interference of the creatinine level with cefpirome. These results indicate that we should be aware of the positive interfering effect of cefpirome when we measure serum creatinine by the Jaffe method, and that the enzymatic method should be widely used to measure serum creatinine levels to eliminate false reactions due to certain chemicals.
- The Keio Journal of Medicineの論文
- 1999-06-01
著者
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Yamada Mitsuhiro
Department of Biology, College of General Education, University of Tokyo
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Kikuchi Hiromi
Department Of Laboratory Medicine Tokyo Electric Power Company Hospital
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Kikuchi Hiromi
Department Of Applied Chemistry Graduate School Of Engineering Tohoku University
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Yamada Mitsuhiro
Departmellt Of Biology C:ollegc Of Gencral Educatioll Universsity Of Tokyo
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Yamada Mitsuhiro
Department Of Laboratory Medicine Tokyo Electric Power Company Hospital
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KABURAKI Junichi
Department of Laboratory Medicine, Tokyo Electric Power Company Hospital
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KAMIKAWARA Minoru
Department of Laboratory Medicine, Tokyo Electric Power Company Hospital
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KONOSU Yumiko
Department of Laboratory Medicine, Tokyo Electric Power Company Hospital
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IWASE Matsumi
Department of Laboratory Medicine, Tokyo Electric Power Company Hospital
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UEHARA Sakae
Department of Laboratory Medicine, Tokyo Electric Power Company Hospital
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Uehara Sakae
Department Of Laboratory Medicine Tokyo Electric Power Company Hospital
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Iwase Matsumi
Department Of Laboratory Medicine Tokyo Electric Power Company Hospital
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Konosu Yumiko
Department Of Laboratory Medicine Tokyo Electric Power Company Hospital
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Kaburaki Junichi
東京電力病院
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Kaburaki Junichi
Department Of Internal Medicine Tokyo Electric Power Company (tepco) Hospital
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Kamikawara Minoru
Department Of Laboratory Medicine Tokyo Electric Power Company Hospital
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