Inhibition of Rat Liver Isoleucyl-tRNA Formation by Microsomal Membrane and the Partial Prevention of This Inhibition by Spermine

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概要

• 論文の詳細を見る

• Rat liver isoleucyl-tRNA formation in the presence of more than 0.6mM Mg^<2+> was inhibited by smooth and rough endoplasmic reticula. The inhibition was partially prevented by ATP, spermine, oligomycin, and Triton X-100. This suggests that microsomal ATPases are responsible for the inhibition of isoleucyl-tRNA formation. Among the microsomal ATPases, an oligomycin-sensitive ATPase was found to be inhibited by spermine. The inhibition of the oligomycin-sensitive ATPase by spermine explains well its partial prevention of the inhibition by endoplasmic reticulum of isoleucyl-tRNA formation.

• 公益社団法人日本薬学会の論文
• 1980-05-25

著者

• 五十嵐 一衛

  Faculty of Pharmaceutical Sciences, Chiba University

• 廣瀬 聖雄

  Faculty of Pharmaceutical Sciences, Chiba University

• 五十嵐 一衛

  千葉大学医学部第一外科

• 五十嵐 一衛

  Faculty Of Pharmaceutical Sciences Chiba University

• 廣瀬 聖雄

  Faculty Of Pharmaceutical Sciences Chiba University

• 田中 誠

  School Of Pharmaceutical Sciences Kitasato University

• 本間 玲子

  Faculty Of Pharmaceutical Sciences Chiba University

• 田中 誠

  Faculty of Pharmaceutical Sciences, Chiba University

• 田中 誠

  Faculty Of Pharmaceutical Sciences Chiba University

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