生薬の品質評価に関する基礎研究(第7報)各種動物胆についてその1

概要

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For the purpose of evaluating the quality of crude drugs derived from animal gall, free, glycine- and taurine-conjugated bile acids were directly analysed by HPLC equipped with a 3α-hydroxysteroid dehydrogenase-immobilized column. Various commercially available galls showed characteristic bile acid composition depending on their sources (snakes, frogs, chickens, pigs, wild boars, cattle and bears), and could be chemically distinguished each other. One of dried snake galls sold in the market was a counterfeit derived from frog gall. Furthermore, some dried bear galls seem likely to be counterfeits derived from cattle gall or mixed with pig and/or cattle gall in comparison with the gall definitely derived from Sus scrofa domesticus BRISSON, Bos taurus domesticus GMELIN, Selenarctos thibetanus japonicus SCHLEGEL and Ursus acros L.
社団法人日本薬学会の論文
1982-08-25