生薬由来イヌリンのマウス網内系の貪食活性化作用

概要

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Physical characters of six inulins isolated from Costi Radix, Taraxaci Radix cum Herba, Atractylodis ovatae Rhizoma, Atractylodis lanceae Rhizoma, Asteris Radix and Dipsaci Radix, and the effects of their inulins on phagocytosis in mouse reticuloendotherial system were investigated. The structures of the inulins from crude drugs were identified only by comparing its spectral evidence with that of authentic samples. Molecular weight, solubility (H_2O, 30℃ for 6 h) and specific rotation ([α]^<28>_D in 1% NaOH aq.) of these inulins were 3500-4000,0.85-1.14 and -20--35,respectively. Among these inulins, three inulins from Taraxaci Radix cum Herba, Atractylodis ovatae Rhizoma and Atractylodis lanceae Rhizoma promoted phagocytosis in mouse reticuloendotherial system in vivo. The correlation between physical characters and the phagocytosis stimulating activity of six inulins was not observed.
公益社団法人日本薬学会の論文
1987-06-25