Selective and Simple Quantification of Metallothionein III in Mouse Brain
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概要
- 論文の詳細を見る
For the selective quantification of metallothionein (MT)-III, MT samples from mouse brain were converted to Hg-MT, then chromatographed using a double (connected-in-tandem) FPLC-gel permeation column system. The chromatogram showed two peaks with a slight overlap. Hg-MT-III was eluted prior to Hg-MT-I and II, probably due to a slightly higher molecular weight. The amount of each isomer was determined from an analysis of the Hg content in each fraction. The present procedure revealed that MT-III in the mouse brain was comparable in quantity to MT-I and II. Thus, MT-III in mouse brain could be selectively quantified at a sub-picomol level.
- 公益社団法人日本薬学会の論文
- 1999-08-31
著者
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YASUTAKE Akira
Biochemistry Section, National Institute for Minamata Disease
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Tohyama Chiharu
Environmental Health Sciences Division, National Institute for Environmental Studies
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SATOH Masahiko
Environmental Health Sciences Division, National Institute for Environmental Studies
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Yasutake Akira
Biochemistry Section Department Of Basic Medical Sciences National Institute For Minamata Disease
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Hirayama Kimiko
Kumamoto University College Of Medical Science
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Satoh Masahiko
Environmental Health Sciences Division National Institute For Environmental Studies
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Tohyama Chiharu
Environmental Health Science Division National Institute For Environmental Studies
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Tohyama Chiharu
Environmental Health Sciences Division National Institute For Environmental Studies
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Tohyama Chiharu
Environ Health Sci Div. Nat'l Inst Environ. Studies
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