Age-Dependent Decreases in Fibrinolytic Enzyme Activities in Serum of Healthy Subjects
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概要
- 論文の詳細を見る
We investigated the age-dependency of serum levels of 9 kinds of proteases. The results showed that the enzymatic activities corresponding to urokinase, plasmin, and thrombin, all involved in blood clotting and fibrinolysis, were inversely correlated with age. This suggests that there is some similarity between the normal process of aging and the pathologic process of Alzheimer's disease. Compared with our previous data on Alzheimer patients, the present results indicate that some derangement in the aging process is involved in the pathogenetic mechanisms of Alzheimer's disease.
- 公益社団法人日本薬学会の論文
- 1994-02-15
著者
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和田 孝雄
Institute Of Microbial Chemistry
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竹内 富雄
Institute of Microbial Chemistry
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小島 蕗子
Institute of Microbial Chemistry
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永井 真知子
Institute of Microbial Chemistry
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原田 滋子
Institute of Microbial Chemistry
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青柳 高明
Department of Hygienic Chemistry, Showa College of Pharmaceutical Sciences
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青柳 高明
Department Of Hygienic Chemistry Showa College Of Pharmaceutical Sciences
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青柳 高明
Department Of Chemistry National Institute Of Health Tokyo
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