Comparison of Characterization among Bordetella Calmodulin-Like Protein, Bovine Brain Calmodulin and Escherichia coli Acyl-Carrier Protein
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概要
- 論文の詳細を見る
We previously reported that Bordetella calmodulin-like protein (CLP), like bovine brain calmodulin (CaM), enhances adenylate cyclase and phosphodiesterase activities. In this communication, antigenic and biochemical characters were compared between CLP and CaM. It was found that anti-CLP and anti-CaM sera obtained reacted with CaM and CLP, respectively. The amino acid composition of CLP was similar to CaM. The similarity was also found in an Escherichia coli acyl-carrier protein (ACP), a CA^<2+>-binding protein. Though the amino acid sequence of N-terminus region of CLP has no significant homology with CaM, ACP has highly homology in its N-terminus similar to CaM. These results suggest that CLP might act as a Ca^<2+>-binding protein, and/or an ACP during the activation of adenylate cyclase and phosphodiesterase.
- 社団法人日本薬学会の論文
- 1997-09-15
著者
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NAGAI Masaaki
Department of Earth and Space Science, Graduate School of Science, Osaka University
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Nagai Masaaki
第一薬科大学 免疫薬品
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Nagai M
Kitasato Inst. Saitama Jpn
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Nagai Masaaki
Division Of Bacterial Vaccines Research Center For Biologicals The Kitasato Institute
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WATANABE Mineo
Department of Microbiology and Biologics, Daiichi College of Pharmaceutical Sciences
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ENDOH Masahiko
Department of Microbiology and Biologics, Daiichi College of Pharmaceutical Sciences
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DANBARA Hirofumi
Department of Microbiology, School of Pharmaceutical Sciences, Kitasato University
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Nagai M
Division Of Quality Control Research Center For Biologicals The Kitasato Institute
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Watanabe M
Department Of Public Health Niigata College Of Medical Technology
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Watanabe M
Division Of Bacterial Vaccines Research Center For Biologicals The Kitasato Institute:(present Addre
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Watanabe Mineo
Department Of Microbiology And Biologics Daiichi College Of Pharmaceutical Sciences
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Endoh Masahiko
Department Of Microbiology And Biologics Daiichi College Of Pharmaceutical Sciences
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Danbara Hirofumi
Department Of Microbiology School Of Pharmaceutical Science Kitasato University
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NAGAI Masaaki
Department of Earth & Space Science, Osaka University
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