IN VITRO CONVERSION OF 2,3-OXIDOSQUALENE INTO DAMMARENEDIOL BY PANAX GINSENG MICROSOMES
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概要
- 論文の詳細を見る
(RS)-[3-^3H]-2,3-Oxidosqualene (1) was converted into (20S)-dammarenediol (2) and not to (20R)-dammarenediol by a microsomal fraction preparaed from the hairy root of Panax ginseng. The enzyme activity was highest at pH 6.0 and was not increased by the addition of any detergents. These properties differed significantly from those of other 2,3-oxidosqualene cyclases reported from higher plants and animals.
- 公益社団法人日本薬学会の論文
- 1997-03-15
著者
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Ohno Yoshimi
Faculty Of Pharmaceutical Sciences The University Of Tokyo
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SHIBUYA MASAAKI
Faculty of Pharmaceutical Sciences, University of Tokyo
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Ebizuka Y
Graduate School Of Pharmaceutical Sciences The Univ. Of Tokyo
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Ebizuka Yutaka
Faculty Of Pharmaceautical Sciences University Of Tokyo
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Shibuya Masaaki
Faculty Of Pharmaceutical Sciences The University Of Tokyo
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Kushiro Tetsuo
Graduate School Of Pharmaceutical Sciences The University Of Tokyo
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KUSHIRO Tetsuo
Faculty of Pharmaceutical Sciences, The University of Tokyo
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