Comparative Immunological Studies of Mutarotases from Mammals

概要

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The antibodies against purified rat and hog kidney mutarotases (type II) were prepared by injecting each of the purified mutarotases into rabbits and were found to quantitatively precipitate the enzyme activities of rat and hog kidney mutarotases, respectively. Immunological cross-reactivity among four forms of both rat and hog kidney mutarotases and among mutarotases from the kidney, liver, and small intestine of 5 species of animals, rat, hog, mouse, beef, and rabbit, was examined by using these antibodies. It was shown that the four forms of mutarotase in rat kidney as well as those in hog kidney were immunologically identical and that the kidney, liver, and small intestine of each species contain very similar enzymes, though there were clear differences between the enzymes from different species.
社団法人日本薬学会の論文
1981-09-25