Metabolism of Flavin Nucleotides. II. Decomposition of Flavin Nucleotides in the Small Intestine.
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Decomposition of flavin nucleotides in the small intestine was studied. Free riboflavin was not decomposed at all in the homogenate of the mucosa of the small intestine. FMN was decomposed to free riboflavin very rapidly in the homogenate and FAD was decomposed to free riboflavin through FMN by two steps in the homogenate of the mucosa of the small intestine. Inhibitors for the decomposition of these flavin nucleotides were studied. EDTA, pyrophosphate, and orthophosphate were found to inhibit decomposition of both FMN and FAD in the homogenate. The minimum concentrations of these inhibitors for 50% or 100% inhibition were obtained.
- 公益社団法人日本薬学会の論文
- 1958-12-15
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