Glycogen Synthesis from the Anomers of Glucose in Rat Diaphragm
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概要
- 論文の詳細を見る
It was examined whether or not a rate-limiting anomerization step is present in the pathway of glycogen synthesis from glucose, in which phosphoglucomutase is known to act specifically on the α anomer of glucose 6-phosphate. Glycogen synthesis from the α and β anomers of D-[U-^<14>C] glucose in rat hemidiaphragms was measured by aerobic incubation in Krebs-Ringer bicarbonate buffer (pH 7.4) at 37℃ for short periods (1 or 3 min) in the presence or absence of insulin (10 mU/ml). There was no statistically significant difference between the rates of glycogen synthesis from the two anomers of glucose under various conditions. These findings suggest that there is no rate-limiting anomerization step in the pathway of glycogen synthesis from glucose in the muscle.
- 公益社団法人日本薬学会の論文
- 1985-07-25
著者
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三輪 一智
名城大学薬学部
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奥田 潤
Department Of Clinical Biochemistry Faculty Of Pharmacy Meijo University
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三輪 一智
Department of Clinical Biochemistry, Faculty of Pharmacy, Meijo University
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藤井 広久
名城大学薬学部
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藤井 広久
Laboratory of Pharmacy, Chubu Rohsai Hospital
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