Studies on Mesoionic Compounds. III. Synthesis of Ψ-3-Aryl-5-imino-3,5-dihydro-1-oxa-2,3,4-triazole Hydrochlorides and Their Derivatives
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概要
- 論文の詳細を見る
Several hitherto unknown mesoionic compounds, Ψ-3-aryl-5-imino-3,5-dihydro-1-oxa-2,3,4-triazole hydrochlorides (III) were synthesized starting from monoarylhydrazines (IV) via cyanohydrazines (V) and nitrosocyanohydrazines (VI). The mesoionic compounds (III) were converted into their N-acyl derivatives (VIII) by treatment with various acylating agents. The free base (VII) was isolated in crystalline from the 3-phenyl homolog of III by treatment with aqueous bicarbonate ; although the corresponding sydnonimine hydrochloride has been known to result in the ring opening under similar conditions.
- 社団法人日本薬学会の論文
- 1971-03-25
著者
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増田 克忠
Faculty Of Pharmaceutical Sciences Toyama Medical And Pharmaceutical University
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増田 克忠
Chemical Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.
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神谷 高明
Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
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柏 謙一
Chemical Research Laboratories, Research and Development Division, Takeda Chemical Industries, Ltd.
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神谷 高明
Chemical Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.
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柏 謙一
Chemical Research Laboratories Research And Development Division Takeda Chemical Industries Ltd.
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