VERSATILE ROUTES TO CHIRAL 4-SUBSTITUTED 2-OXAZOLIDINONES AND α-AMINO ACIDS. USE OF CHIRON, [4+2] CYCLOADDUCTS OF DIALKYL AZODICARBOXYLATES AND 2-OXAZOLONES
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概要
- 論文の詳細を見る
The thermal reaction of 3-[(1S)-2-alkoxyl-1-apocamphanecarbonyl]-2-oxazolones with dialkyl azodicarboxylates results in exclusive formation of [4+2] type cycloadducts with moderate levels of diastereofacial selection, which serve as versatile chiral synthons for a wide variety of 4-alkyl and 4-aryl-2-oxazolidinones as well as α-amino acids.
- 公益社団法人日本薬学会の論文
- 1992-04-25
著者
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丸林 信洋
Research Laboratories, Yoshitomi Pharmaceutical Industries, Ltd.,
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國枝 武久
Faculty of Pharmaceutical Sciences, University of Tokyo
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丸林 信洋
Yoshitomi Pharmaceutical Co., Ltd.,
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國枝 武久
Faculty Of Pharmaceutical Sciences Kumamoto University
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丸林 信洋
Research Laboratories Yoshitomi Pharmaceutical Industries Ltd.
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松永 浩文
Faculty of Pharmaceutical Sciences, Kumamoto University
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石塚 忠男
Faculty of Pharmaceutical Sciences, Kumamoto University
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國枝 武久
Kumamoto Univ. Kumamoto Jpn
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石塚 忠男
Fac. Of Medical And Pharmaceutical Sciences Kumamoto Univ.
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松永 浩文
Faculty Of Pharmaceutical Sciences Kumamoto University
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