Studies on the Biosynthesis of Corrinoids and Porphyrinoids. III. The Origin of Amide Nitrogen of Vitamin B_<12>
スポンサーリンク
概要
- 論文の詳細を見る
To clarify the origin of amide-nitrogen of vitamin B_<12>, [1-^<13>C]aminolevulinic acid (ALA) and L-[amide-^<15>N]glutamine were administered to P. shermanii. The ^<13>C-nuclear magnetic resonance spectrum of the vitamin B_<12> subsequently isolated showed distinct ^<13>C-^<15>N coupling and isotope shift at six amide carbons. However, the C-57 amide carbon showed neither coupling, nor shift. Thus, it was concluded that the nitrogens of 6 amides of the side chain were derived from glutamine and the C-57 amide nitrogen was from threonine.
- 社団法人日本薬学会の論文
- 1990-09-25
著者
-
車谷 勝行
Department of Medicinal Chemistry, Meiji College of Pharmacy
-
梶原 正宏
Department of Medicinal Chemistry, Meiji College of Pharmacy
-
車谷 勝行
Department Of Medicinal Chemistry Meiji College Of Pharmacy
-
梶原 正宏
Department Of Medicinal Chemistry Meiji College Of Pharmacy
関連論文
- Synthesis of [^C]Phenacetin and Its Application ot the Breath Test for the Diagnosis of Liver Disease
- Biosynthesis of Corrinoids and Porphyrinoids. VII. Uroporphyrins from Saccharopolyspora erythraea
- Direct Injection Method for Quantitation of δ-Aminolevulinic Acid in Urine by High-Performance Liquid Chromatography
- Biological Resolution of (2RS)-Tocopherol and (2RS)-Tocopheryl Acetate
- Stereochemical Studies on the Formation of Melanin by Monophenol Monooxygenase
- Analysis of Amino Acids by High-Performance Liquid Chromatography with Circular Dichroism Detection
- Biosynthesis of Corrinoids and Porphyrinoids. IX. Studies on the Origin of Oxygen of Uroporphyrinogen III in Arthrobacter hyalinus
- Biosynthesis of Erythromycin : Origin of the Methyl Protons
- ONE-POT SYNTHESIS OF DIHYDROXYCYCLOPENTANES FROM ALLYLSULFONES AND CHIRAL DIEPOXIDES
- Carbon-13 Nuclear Magnetic Resonance Studies of the Biosynthesis of Hyaluronic Acid
- Direct Monitoring by Carbon-13 Nuclear Magnetic Resonance Spectroscopy of the Metabolism and Metabolic Rate of ^C-Labeled Compounds in Vivo
- Studies on the Syntheses of Heterocyclic Compounds. DCXLI A Convenient Synthesis of Hexadehydroyohimbine and a Total Synthesis of Yohimbine
- Studies on the Syntheses of Tetracycline Derivatives. I. Thermolytic Cycloaddition of o-Quinodimethanes with Naphthoquinone
- Studies on the Biosynthesis of Corrinoids and Porphyrinoids. X. Biosynthetic Studies of Bacteriochlorophyll-a in Rhodopseudomonas spheroides : Incorporation of ^2H-, ^C- and ^N-Labeled Substrates and Origin of the Hydrogen Atoms
- Studies of the Biosynthesis of Corrinoids and Porphyrinoids. IV. Biosynthesis of Chlorophyll in Euglena gracilis
- Studies on the Biosynthesis of Corrinoids and Porphyrinoids. III. The Origin of Amide Nitrogen of Vitamin B_
- Direct Observation of Enzymatic Transformation of δ-Aminolevulinic Acid to Porphobilinogen and Uroporphyrinogen in a Cell-Free System by Carbon-13 Nuclear Magnetic Resonance Spectroscopy
- ビタミンB_生合成機構解明の現状
- Studies on the Biosynthesis of Corrinoids and Porphyrinoids.II. : The Origin of Nitrogen of Vitamin B_
- 89(P2-19) クロロフィル・バクテリオクロロフィルの生合成(ポスター発表の部)
- Studies on the Biosynthesis of Corrinoids and Porphyrinoids. I : The Labeling of Oxygen of Vitamin B_
- 2-I-45 ビタミンB_の生合成 : ヘテロ原子の由来について(第41回大会一般研究発表)
- Proton Nuclear Magnetic Resonance (^1H-NMR) Signal Assignment of Vitamin B_ Based on Normal Two-Dimensional NMR and Feeding Experiments
- 19 コリン・ポルフィリン類の生合成(ポスター発表の部)