N^3-BENZYLURIDINE EXERTS HYPNOTIC ACTIVITY IN MICE
スポンサーリンク
概要
- 論文の詳細を見る
N^3-Benzyluridine (I), a derivative of uracil (II) or uridine (III), has hypnotic effect on mice. The hypnotic effect of I was effected by intracerebroventricular injection. The response was dose-dependent with doses of 1.5-4.0 μmol/mouse. Further, I significantly prolonged pentobarbital-induced sleep in mice. In the same doses, II and III have no hypnotic or sleep-prolonging effects. These results suggest that III may be a sleep-promoting substance basically, as reported by Komoda et al.
- 公益社団法人日本薬学会の論文
- 1985-09-25
著者
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HO Ing
University of Mississippi Medical Center
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舘岡 裕二
Shinshin Chemical Industry Co. Ltd.
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渡辺 和人
School of Pharmacy, Hokuriku University
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Ho Ing
ミシシッピ大学医学部薬毒理学教室
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Tateoka Yuji
Department Of Hygienic Chemistry Faculty Of Pharmaceutical Sciences Hokuriku University
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