Structures of Three New 2-Arylbenzofuran Derivatives from the Chinese Crude Drug "Sang-Bai-Pi" (Morus Root Bark)

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概要

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• Three new 2-arylbenzofuran derivatives named mulberrofurans K, N, and O were isolated from the extract of the Chinese crude drug "Sang-Bai-Pi" (Japanese name "Sohakuhi"), the root bark of Morus sp. (Moraceae). The structures of mulberrofurans K, N and O were shown to be 1,2,and 3,respectively, on the basis of spectral and chemical evidence. Mulberrofurans K and O are optically active and may be regarded biogenetically as Diels-Alder type adducts of chalcone derivatives and a dehydroprenyl-2-arylbenzofuran derivative. Furthermore, mulberrofuran K seems to be derived from the Diels-Alder type adduct by intramolecular ketalization.

• 公益社団法人日本薬学会の論文
• 1985-12-25

著者

• 羽野 芳生

  Faculty of Pharmaceutical Sciences, Toho University

• 野村 太郎

  Faculty of Pharmaceutical Sciences, Toho University

• 野村 太郎

  Faculty Of Pharmaceutical Sciences Toho University

• 野村 太郎

  東邦大 薬

• 羽野 芳生

  東邦大薬

• 河野 英明

  東邦大・薬:(現)サンド薬品

• 井藤 正人

  Faculty Of Pharmaceutical Sciences Toho University

• 河野 英明

  Faculty of Pharmaceutical Sciences, Toho University

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