Ethanol Enhancement of Cytochrome P-450 Content in Yeast, Saccharomyces cerevisiae D7
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概要
- 論文の詳細を見る
When Saccharomyces cerevisiae D7 was cultured in yeast extract-proteose peptone-2% glucose (YPG) liquid medium supplemented with 1.5 and 3% ethanol, the maximum cytochrome P-450 contents in the whole cell suspension were 1.5 and 1.3 times higher, respectively, than that in YPG medium without ethanol. The addition of 6% ethanol to YPG medium decreased the growth rate and final cell population of the yeast markedly, while the cellular content of cytochrome P-450 was similar to that of cells grown in YPG medium. Though the logarithmic phase was extended under glucose-repressed conditions in YPG medium containing 10% glucose, there was no increase in the cytochrome P-450 content compared with the cells grown on 2% glucose. In the medium in which 2% ethanol was the sole carbon and energy source (YPE medium), the growth rate and final cell population of the yeast showed a marked decrease compared with those of cells grown on glucose. Cytochrome P-450 was not detectable in the cells grown on ethanol.
- 公益社団法人日本薬学会の論文
- 1984-04-25
著者
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森田 全
Division Of Environmental Health Sciences University Of Shizuoka
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三渕 一二
Faculty of Pharmacy and Pharmaceutical Sciences, University of Fukuyama
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三渕 一二
Shizuoka College of Pharmacy
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森田 全
Shizuoka College of Pharmacy
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三渕 一二
Faculty Of Pharmacy And Pharmaceutical Sciences University Of Fukuyama
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