Synthesis of D-Glucuronic Acid Derivatives of 5-Fluorouracil having O-Glycosidic Linkage

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概要

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• 5-Fluorouracil-4-O-glucuronic acid derivatives (V, VII) were synthesized by a condensation reaction of the silver salt of 2-benzyloxy-5-fluoro-4-pyrimidone with methyl 1-bromo-1-deoxy-2,3,4-tri-O-acetyl-α-D-glucopyranuronate and subsequent careful removal of the protecting group.

• 公益社団法人日本薬学会の論文
• 1977-09-25

著者

• 清水 文治

  Central Research Laboratories of Sankyo Co., Ltd.

• 金子 正勝

  Central Research Laboratories of Sankyo Co., Ltd.

• 木村 美佐子

  Central Research Laboratories of Sankyo Co., Ltd.

• 木村 美佐子

  Chemical Research Laboratories:sankyo Company Ltd.

• 田中 宏幸

  Central Research Laboratories Sankyo Co., Ltd.

• 田中 宏幸

  Central Research Laboratories Sankyo Co. Ltd.

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• Synthesis of D-Glucuronic Acid Derivatives of 5-Fluorouracil having O-Glycosidic Linkage

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