Studies on Synthetic Nucleotides. II. A Direct Synthetic Method of Ribonucleotides.
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概要
- 論文の詳細を見る
A direct synthetic method of purine and pyrimidine nucleotides has been described. Condensation of III with 2,3-di-O-benzoyl-5-diphenylphosphoryl-D-ribofuranosyl bromide in dimethylformamide at 40〜50°, followed by removal of the protecting groups gave AMP. Several other purine and pyrimidine nucleotides were also obtained by the same method mentioned above. In those cases, nitromethane, dimethylsulfoxide, acetonitrile and dimethylacetamide were effective for the reaction as solvents.
- 社団法人日本薬学会の論文
- 1967-12-25
著者
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清水 文治
Central Research Laboratories of Sankyo Co., Ltd.
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宮木 美知子
Central Research Laboratories Sankyo Co. Ltd.
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浅井 素次
Central Research Laboratories, Sankyo Co., Ltd.
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浅井 素次
Central Research Laboratories Sankyo Co. Ltd.
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清水 文治
Central Research Laboratories Sankyo Co. Ltd.
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