Infrared Spectra of Pyrazine-and Pyridine-carboxylic Acid and Their Derivatives.
スポンサーリンク
概要
- 論文の詳細を見る
Infrared absorption spectra of pyridine- and pyrazine-carboxylic acids have following characteristic absorptions. 1) There are broad absorption bands with peaks at 2450 and 1900 cm^<-1>. The former shifts to around 1900 cm^<-1> by deuteration but the latter does not. 2) Absorptions for O-H in-plane deformation and C-O stretching vibration are present at 1340〜1300 cm^<-1> and 1310〜1260 cm^<-1>, and shift respectively to 1360〜1340 cm^<-1> and 1080〜1020 cm^<-1> by deuteration. 3) There is no absorption band for O-H out-of-plane deformation and that for [chemical formula] is present at around 700 cm^<-1>. These characteristic absorptions can be explained by the structure (II) with intramolecular hydrogen bonding for nicotinic and isonicotinic acids, and the structures (VI and VII) with intramolecular hydrogen bonding for picolinic and pyrazinic acids possessing a carboxyl in the position alpha to ring nitrogen. The hydrochloride of pyridinecarboxylic acids and 2,6-disubstituted isonicotinic acid derivatives possess the structure (II) same as that of ordinary carboxylic acids.
- 社団法人日本薬学会の論文
- 1959-03-20
著者
-
浅井 素次
Central Research Laboratories, Sankyo Co., Ltd.
-
吉田 茂
Takamine Research Laboratory, Sankyo Co., Ltd.
-
吉田 茂
Takamine Research Laboratory Sankyo Co. Ltd.
-
浅井 素次
Takamine Research Laboratory, Sankyo Co., Ltd.
-
浅井 素次
Central Research Laboratories Sankyo Co. Ltd.
関連論文
- Studies on Synthetic Nucleotides. II. A Direct Synthetic Method of Ribonucleotides.
- Preparation of L-β-Ribonucleosides and L-β-Ribonucleotides
- Studies on the Allied Compounds of Vitamin B_1. XXIII. Synthesis of N-Acyl-O, S-dibenzoylthiamines.
- Studies on Allied Compounds of Vitamin B_1. XXI. The Structure of Dihydrothiamine. (2).
- Studies on the Allied Compounds of Vitamin B_1. XX. The Structure of Dihydrothiamine. (1)
- Infrared Spectra of Benzoyl Halides and their Substituted Derivatives.
- On the CH Out-of-plane Vibrations and Extra Bands of Benzoic Acid, Benzoic Acid Esters, Benzoyl Chloride, and their para-Substituted Derivatives
- Infrared Spectra of Pyrazine-and Pyridine-carboxylic Acid and Their Derivatives.
- Studies on the Allied Compounds of Vitamin B_1. XXII. Acylation of Thiothiamine and Its Derivatives.
- カルボン酸アルカミンエステルアンモニウム塩の合成研究(第2報)
- ビタミンB_1関係化合物の研究(第17報) : N-置換Thiocarbamateの構造
- Studies on Acetylenic Compounds. XXIX. A New Method for Synthesis of DL-Ribose.
- Studies on Synthetic Nucleotides. I. A Convenient Synthesis of Ribonucleotides.
- A Convenient Synthesis of Nucleotides
- Studies on Synthetic Nucleotides. IV. Preparation of L-β-Ribonucleosides and L-β-Ribonucleotides.
- Studies on Acetylenic Compounds. XXXVI. Total Synthesis of Ethyl 3-Amino-3-deoxy-β-DL-arabinofuranoside.