Analytical Chemical Studies on Steroids. VII. The Zimmermann Complexes Derived from i-Androstanolone and Its Related 17-Oxosteroids
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概要
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The structure of Zimmermann complexes produced from i-androstanolone (6β-hydroxy-3α, 5α-cycloandrostan-17-one) was investigated. By means of preparative thinlayer chromatography two complexes were successfully isolated and were elucidated as 6β-hydroxy-16ξ-(2,4-dinitrophenyl)-3α, 5α-cycloandrostan-17-one, m.p. 113〜116°, and 3β-chloro-16ξ-(2,4-dinitrophenyl)androst-5-en-17-one, m.p. 192〜194°, respectively. These results revealed that the former complex would be transformed into the latter one by contact with hydrochloric acid. On the other hand dehydroisoandrosterone gave Zimmermann complex, 3β-hydroxy-16ξ-(2,4-dinitrophenyl)androst-5-en-17-one, m.p. 186〜188°, as a single product.
- 公益社団法人日本薬学会の論文
- 1965-12-25
著者
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加藤 元彦
Research And Development Division Kikkoman Corporation
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南原 利夫
Faculty of Pharmaceutical Sciences, School of Medicine, Hokkaido University
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加藤 元彦
Faculty of Pharmaceutical Sciences, University of Tokyo
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