Studies on Acetylenic Compounds. XX. Carbon-Carbon Alkylation with Acetylenic Mannich Base.
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概要
- 論文の詳細を見る
It was found that methyl iodide of acetylenic Mannich base reacted with active methylene compounds to form alkylated acetylenic compounds with a loss of tertiary amine. Various acetylenic compounds may be prepared by this method. It seems likely that such alkylation reactions proceed mainly by S_N-1 mechanism in alcohol and mainly by S_N-2 mechanism in dibutyl ether.
- 公益社団法人日本薬学会の論文
- 1962-02-25
著者
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岩井 一成
Takamine Laboratory, Sankyo Co., Ltd.
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平岡 哲夫
Takamine Research Laboratory, Sankyo Co., Ltd.
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平岡 哲夫
三共(株)総合研究所
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岩井 一成
Central Research Laboratories Sankyo Co. Ltd.
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