Studies on Acetylenic Compounds. XXXIII. A New Synthetic Method for Aminoacetylenic Compounds.
スポンサーリンク
概要
- 論文の詳細を見る
A new and convenient route for the synthesis of various kinds of aminoacetylenes has been devised with Grignard reaction of aminoethers using acetylenemagnesium bromide. In the various cases examined, the yields range was 26〜76%. Both N, N-di (2-propynyl) amine- an 1,4-di (2-propynyl) piperazine derivatives could be produced by this reaction, but in latter N, N-di (2-propynyl) methylamine derivative due to low reactivity of N, N-bis (butoxymethyl) methylamine (III) the reaction time was prolonged. Furthermore, by this reaction acetylenic aminoalcohols were obtained from cyclic aminoethers.
- 公益社団法人日本薬学会の論文
- 1963-08-25
著者
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岩井 一成
Takamine Laboratory, Sankyo Co., Ltd.
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由良 靖雄
Takamine Laboratory, Sankyo Co., Ltd.
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由良 靖雄
Central Research Laboratories Sankyo Co. Ltd.
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岩井 一成
Central Research Laboratories Sankyo Co. Ltd.
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