Potential Anti-cancer Agents. IV. 3-Substituted 6-Chloropyridazine 1-Oxides.
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概要
- 論文の詳細を見る
When 3,6-dichloropyridazine and 3-alkoxy-6-chloropyridazines were oxidized with monoperphthalic acid or hydrogen peroxide-glacial acetic acid, the corresponding Noxides were produced. With the latter reagent, however, 6-substituted-3 (2H)-pyridazinones gave rise to byproducts. The N-oxidation of 3-alkoxy-6-chloropyridazines was shown to take place at the 1-position of the molecules. By catalytic dehalogenation, several 3-alkoxypyridazine 1-oxides were also prepared.
- 公益社団法人日本薬学会の論文
- 1962-10-25
著者
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板井 孝信
Showa College of Pharmaceutical Sciences
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板井 孝信
National Institute of Hygienic Sciences
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佐子 茂
National Institute of Hygienic Sciences
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佐子 茂
National Institute Of Hygienic Sciences:(present Address) Ukima Plant Chugai Pharmaceutical Co. Ltd.
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