Syntheses of Pyridazine Derivatives. III. 4-or 5-Chloro-3,6-dimethylpyridazine 1-Oxide.

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概要

• 論文の詳細を見る

• N-Oxidation of 4-chloro-3,6-dimethylpyridazine (II) with monoperphthalic acid gave 4-chloro-3,6-dimethylpyridazine 1-oxide (III) and 5-chloro-3,6-dimethylpyridazine 1-oxide (IV). The order of reactivity of these chloro-compounds in nucleophilic substitution are IV>II>III.

• 公益社団法人日本薬学会の論文
• 1963-03-25

著者

• 佐子 茂

  National Institute of Hygienic Sciences

• 佐子 茂

  National Institute Of Hygienic Sciences:(present Address) Ukima Plant Chugai Pharmaceutical Co. Ltd.

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• Potential Anti-cancer Agents. III. 3,6-Disubstituted 4-Nitropyridazine 1-Oxides.
• Potential Anticancer Agents. XIII. Reaction of 3,6-Dimethylpyridazine 1-Oxide and Methylpyridazine 1-Oxides with Benzaldehyde.
• Syntheses of Pyridazine Derivatives. IV. Halogenopyridazine 1-Oxides
• Syntheses of Pyridazine Derivatives. III. 4-or 5-Chloro-3,6-dimethylpyridazine 1-Oxide.
• Syntheses of Pyridazine Derivatives. II. The Reactivity of Chlorine Atom in 3- or 6-Position of Chloropyridazine 1-Oxide.
• Syntheses of Pyridazine Derivatives. I. The Reactivity of Chlorine Atoms in 3- and 6-Positions of 3,6-Dichloropyridazine 1-Oxide.

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