Syntheses of Pyridazine Derivatives. IV. Halogenopyridazine 1-Oxides
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概要
- 論文の詳細を見る
N-oxidation of 5-amino-3,4-dichloropyridazine and 4-amino-3,5-dichloropyridazine gave their 1-oxides. The amino groups on 3-, 4-, 5-, and 6-positions of pyridazine 1-oxide were substituted with chlorine or bromine by diazotization, but yield of 3-bromopyridazine 1-oxide was poor. 5-Amino-3,4-dichloropyridazine 1-oxide is usable as the starting material for the preparation of 5-substituted pyridazine 1-oxides.
- 公益社団法人日本薬学会の論文
- 1966-03-25
著者
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佐子 茂
National Institute of Hygienic Sciences
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佐子 茂
National Institute Of Hygienic Sciences:(present Address) Ukima Plant Chugai Pharmaceutical Co. Ltd.
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- Potential Anticancer Agents. XIII. Reaction of 3,6-Dimethylpyridazine 1-Oxide and Methylpyridazine 1-Oxides with Benzaldehyde.
- Syntheses of Pyridazine Derivatives. IV. Halogenopyridazine 1-Oxides
- Syntheses of Pyridazine Derivatives. III. 4-or 5-Chloro-3,6-dimethylpyridazine 1-Oxide.
- Syntheses of Pyridazine Derivatives. II. The Reactivity of Chlorine Atom in 3- or 6-Position of Chloropyridazine 1-Oxide.
- Syntheses of Pyridazine Derivatives. I. The Reactivity of Chlorine Atoms in 3- and 6-Positions of 3,6-Dichloropyridazine 1-Oxide.