Synthesis of Pyrazine Derivatives. I. Reactions of 2,5-Dimethylpyrazine N-Oxides with Acid Chlorides
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概要
- 論文の詳細を見る
When N-oxides of 2,5-dimethylpyrazine and their 3,6-disubstituted (chlorine or alkoxy) derivatives were reacted with phosphorus oxychloride, various compounds substituted by chlorine on the nucleus and/or on the methyl group (s) were produced in low yields. Accordingly, a few kinds of other acid chlorides were examined to elevate the yields, but no one could improve the results. Chlorinated compounds thus obtained were converted to their corresponding alkoxy derivatives (methoxy, ethoxy or benzyloxy).
- 公益社団法人日本薬学会の論文
- 1975-11-25
著者
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板井 孝信
Showa College of Pharmaceutical Sciences
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松浦 功文
Showa College of Pharmaceutical Sciences
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猪又 美代子
Showa College of Pharmaceutical Sciences
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及川 すみ子
Showa College of Pharmaceutical Sciences
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進 康
Showa College of Pharmaceutical Sciences
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