Potential Anti-cancer Agents. IX. Nitration of Pyridazine 1-Oxide. (2).
スポンサーリンク
概要
- 論文の詳細を見る
Nitration of pyridazine 1-oxide (I) with acyl nitrate afforded two kinds of β-nitropyridazine 1-oxide, i. e., 3-nitropyridazine 1-oxide (III) as a main product and 5-nitropyridazine 1-oxide (IV) as a poorly yielded by-product. Structural correlations of those nitro compounds to known pyridazine derivatives were achieved by catalytic hydrogenations or nucleophilic displacement reactions of the active nitro group. Furthermore, some nucleophilic substitution reactions of III and 3-chloropyridazine 1-oxide were described.
- 公益社団法人日本薬学会の論文
- 1963-03-25
著者
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夏目 幸子
Central Research Laboratories, Sankyo Co., Ltd.
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板井 孝信
Showa College of Pharmaceutical Sciences
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板井 孝信
National Institute of Hygienic Sciences
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夏目 幸子
National Intitute of Hygienic Sciences
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夏目 幸子
Central Research Laboratories Sankyo Co. Ltd.
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