Researches on Chemotherapeutic Drugs against Viruses. XXXII. Studies on the Synthesis and the Antiviral Effect of N-Alkanoyl-5-acetamido-8-quinolinesulfonamide.

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概要

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• The six compounds of N-alkanoyl-5-acetamido-8-quinolinesulfonamide were synthesized and their antiviral effect was tested by employing the Nakayama strain of Japanese B encephalitis virus. The decanoyl derivative was more effective in vitro than PANS-610 or N-decanoyl-8-ethoxy-5-quinolinesulfonamide. Moreover, the decanoyl derivative was found to possess significant in vivo effect against the Nakayama strain.

• 公益社団法人日本薬学会の論文
• 1960-10-25

著者

• 川畑 潤三

  Pharmaceutical Institute, Keio-Gijuku University

• 豊島 滋

  Pharmaceutical Institute, Keio-Gijuku University

• 豊島 滋

  慶大・医学部・薬化学研究所・化学療法部門

• 豊島 滋

  Pharmaceutical Institute Keio-gijuku University

• 川畑 潤三

  Pharmaceutical Institute Keio-gijuku University

• 鯉淵 弘子

  Pharmaceutical Institute, Keio-Gijuku University

• 鯉淵 弘子

  Pharmaceutical Institute Keio-gijuku University

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