Synthesis and Cytotoxic Activity of 1-Alkoxy- and 1-Amino-2-hydroxy-1,2-dihydroacronycine Derivatives
スポンサーリンク
概要
- 論文の詳細を見る
Sixteen new derivatives of the natural alkaloid acronycine, bearing 1-alkoxy or 1-amino and 2-hydroxy groups, were synthesized in order to clarify the role of the C-1 substitution. Studies on the cytotoxic activity of compounds 4-19 were carried out in vitro on L-1210 cells. Structure-activity relationships are discussed.
- 公益社団法人日本薬学会の論文
- 1999-05-15
著者
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Koch Michel
Laboratoire De Pharmacognosie De I'universite Rene Descartes U.m.r. C.n.r.s. N° 8638 Faculte De
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Michel Sylvie
Laboratoire De Pharmacognosie De I'universite Rene Descartes U.m.r. C.n.r.s. N° 8638 Faculte De
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Koch M
Univ. Rene Descartes Paris Fra
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TILLEQUIN Francois
Laboratoire de Pharmacognosie de l'Universite Paris Descartes
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PIERRE Alain
Institut de Recherches Servier, Division Recherche Cancerologie
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SKALTSOUNIS Alexios-Leandros
University of Athens, Department of Pharmacy, Division of Pharmacognosy
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ATASSI Ghanem
Institut de Recherches "SERVIER"
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MAGIATIS Prokopios
Laboratory of Pharmacognosy, University of Athens
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MITAKU Sofia
Laboratory of Pharmacognosy, University of Athens
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SKALTSOUNIS Alexios-Leandros
Laboratory of Pharmacognosy, University of Athens
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Pierre Alain
Institut De Recherches Servier Division Recherche Cancerologie
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Mitaku S
Laboratory Of Pharmacognosy Department Of Pharmacy University Of Athens
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Atassi G
Inst. Res. Servier Suresnes Fra
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Tillequin Francois
Laboratoire De Pharmacognosie De L'universite Paris Descartes
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Tillequin F
Laboratoire De Pharmacognoise De 1'universite Rene Descartes Umr/cnrsn ^○8638 Faculte Des Scien
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Mitaku Sofia
Laboratory Of Pharmacognosy Department Of Pharmacy University Of Athens
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Magiatis Prokopios
Laboratory Of Pharmacognosy Department Of Pharmacy University Of Athens
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Skaltsounis A‐l
University Of Athens Department Of Pharmacy Division Of Pharmacognosy
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Skaltsounis Alexios-leandros
Laboratory Of Pharmacognosy Department Of Pharmacy University Of Athens
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