(-)-14β-Acetoxymatrine and (+)-14α-Acetoxymatrine, Two New Matrine-Type Lupin Alkaloids from the Leaves of Sophora tonkinensis

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概要

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• Two new lupin alkaloids, which are the first ester derivatives of matrine-type lupin alkaloids, (-)-14β-acetoxymatrine and (+)-14α-acetoxymatrine, were isolated from the leaves of Sophora tonkinensis along with fourteen known lupin alkaloids : 17-oxo-α-isosparteine, (-)-sophocarpine, (+)-matrine, (-)-14β-hydroxymatrine, (+)-14α-hydroxymatrine, 13,14-dehydrosophoranol (5α-hydroxysophocarpine), (+)-sophoranol, (+)-9α-hydroxymatrine, lamprolobine, (+)-5α, 9α-dihydroxymatrine, (-)-baptifoline, (+)-matrine N-oxide, (+)-sophocarpine N-oxide, and (+)-sophoranol N-oxide.

• 公益社団法人日本薬学会の論文
• 1999-03-15

著者

• Ohmiya Shigeru

  中華人民共和国

• Ohmiya S

  Hoshi Univ. Tokyo Jpn

• Li J‐s

  Beijing University Of Traditional Chinese Medicine

• Li Jia-shi

  Beijing University Of Traditional Chinese Medicine

• Kubo H

  New Product Research Laboratories Ii Daiichi Pharmaceutical Company Ltd.

• KUBO Hajime

  Faculty of Medicinal Chemistry; Hoshi University

• KUBO Hajime

  Institute of Medicinal Chemistry, Hoshi University

• HIGASHIYAMA Kimio

  Institute of Medicinal Chemistry, Hoshi University

• OHMIYA Shigeru

  Institute of Medicinal Chemistry, Hoshi University

• KOMIYA Hideaki

  Institute of Medicinal Chemitry, Hoshi University

• XIAO Ping

  Institute of Medicinal Chemistry, Hoshi University

• YAN Yuning

  Department of Pharmacognosy, Beijing University of Traditional Chinese Medicine

• LI Jia-shi

  Department of Pharmacognosy, Beijing University of Traditional Chinese Medicine

• Xiao Ping

  Institute Of Medicinal Chemistry Hoshi University

• Yan Yuning

  Department Of Pharmacognosy Beijing University Of Traditional Chinese Medicine

• Higashiyama Kimio

  Institute Of Medicinal Chemistry Hoshi University

• Higashiyama K

  Faculty Of Pharmaceutical Sciences Okayama University

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