Automatic System for the Assay of Guanidino Compounds to Assess Uremic Status and Effect of Hemodialysis
スポンサーリンク
概要
- 論文の詳細を見る
An automated HPLC system coupled with fluorometry was established for the sensitive, rapid and accurate assay of serum guanidines. Naturally fluorescent materials characteristic of the sera of uremic patients (uremic fluorescences) which interfere with the assay were removed simultaneously with deproteinization. Application of this method revealed that the uremic patients who are capable of excreting urine under hemodialysis therapy show low serum guanidinosuccinic acid levels. The interval between hemodialysis sessions in one of these patients was prolonged while monitoring guanidinosuccinic acid level using the present method without any hazardous effect.
- 公益社団法人日本薬学会の論文
- 1998-11-15
著者
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Kinoshita Takayoshi
Analytical Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
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Kubo H
New Product Research Laboratories Ii Daiichi Pharmaceutical Company Ltd.
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KUBO Hajime
Faculty of Medicinal Chemistry; Hoshi University
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KUBO Hiroaki
School of Pharmaceutical Sciences, Kitasato University
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SUZUKI Junko
School of Agriculture, Ibaraki University
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Kinoshita T
School Of Pharmaceutical Sciences Kitasato Univ.
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NOHARA Yukio
Faculty of Pharmaceutical Sciences, Teikyo University
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MATSUMOTO Gou
Department of Medicine, Matsumoto Hospital
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KINOSHITA Toshio
School of Pharmaceutical Sciences, Kitasato University
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HANAI Toshihiko
International Institute of Technological Analysis, Health Research Foundation
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IINUMA Fumio
Faculty of Pharmaceutical Sciences, Teikyo University
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NOHARA Yukio
School of Pharmaceutical Sciences, Kitasato University
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IINUMA Fumio
School of Pharmaceutical Science, Teikyo University
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Iinuma F
Faculty Of Pharmaceutical Sciences Teikyo University
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Matsumoto Gou
Department Of Medicine Matsumoto Hospital
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Hanai Toshihiko
International Institute Of Technological Analysis Health Research Foundation
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Hanai Toshihiko
International Inst. Of Technological Analysis Health Res. Foundation
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Kinoshita Toshio
School Of Pharmaceutical Sciences Kitasato University
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Kubo Hiroaki
School Of Pharmaceutical Sciences Kitasato University
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Suzuki Junko
School Of Agriculture Ibaraki University
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Suzuki J
School Of Pharmacy Kitasato Univ.
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